02877cam a2200337 4500 366161684 TxAuBib 20150410120000.0 141024s2015||||||||||||||||||||||||eng|u 2014034832 9781476717777 hardcover : acid-free paper 147671777X hardcover : acid-free paper 9781476717791 softcover : acid-free paper 1476717796 softcover : acid-free paper DLC eng DLC TxAuBib Genova, Lisa. Inside the O'Briens : a novel / Lisa Genova. 1st Gallery Bks. hardcover ed. New York City : Gallery Books, 2015. 343p. ; 22cm. "From award-winning, New York Times bestselling author and neuroscientist Lisa Genova comes a powerful new novel that does for Huntington's Disease what her debut Still Alice did for Alzheimer's. Joe O'Brien is a forty-four-year-old police officer from the Irish Catholic neighborhood of Charlestown, Massachusetts. A devoted husband, proud father of four children in their twenties, and respected officer, Joe begins experiencing bouts of disorganized thinking, uncharacteristic temper outbursts, and strange, involuntary movements. He initially attributes these episodes to the stress of his job, but as these symptoms worsen, he agrees to see a neurologist and is handed a diagnosis that will change his and his family's lives forever: Huntington's Disease. Huntington's is a lethal neurodegenerative disease with no treatment and no cure. Each of Joe's four children has a 50 percent chance of inheriting their father's disease, and a simple blood test can reveal their genetic fate. While watching her potential future in her father's escalating symptoms, twenty-one-year-old daughter Katie struggles with the questions this test imposes on her young adult life. Does she want to know? What if she's gene positive? Can she live with the constant anxiety of not knowing? As Joe's symptoms worsen and he's eventually stripped of his badge and more, Joe struggles to maintain hope and a sense of purpose, while Katie and her siblings must find the courage to either live a life "at risk" or learn their fate. Praised for writing that "explores the resilience of the human spirit" (The San Francisco Chronicle), Lisa Genova has once again delivered a novel as powerful and unforgettable as the human insights at its core"-- Provided by publisher. 20150410. Huntington's disease Patients Fiction. Police Massachusetts Fiction. Terminally ill Fiction. FICTION / Contemporary Women. FICTION / Medical. FICTION / General. Medical fiction. Domestic fiction.